An active ingredient in whitening pieces has been shown to damage the protein-rich tooth layer that connects with the nerves of your teeth.
Presenting their preliminary findings at this year’s Experimental Biology fulfill, researchers found that hydrogen peroxide( H2O2 ), the main component of over-the-counter whitening rows, may damage the second-layer dentin tissue.
The human tooth is made use of three strata: the outer enamel, the dentin coating, and connective tissue that binds the root to the gum. Enamel contains little protein, whereas dentin represents up most of the tooth and has high levels of protein, 95 percent of which is collagen. Preliminary sees from three studies suggest that when whitening pieces are utilized, hydrogen peroxide are useful in whitening rows can penetrate the enamel to break collagen within the dentin layer.
“We sought to further distinguish what the hydrogen peroxide was doing to collagen, ” said lead researcher Kelly Keenan in a statement. “We use entire teeth for the studies and focused on the impact hydrogen peroxide has on the proteins.”
In the first study, researchers considered teeth with either one or three rounds of over-the-counter whitening pieces that had been processed with artificial saliva and refined with EDTA, a molecule that binds and protrudes to calcium. The teeth were left in this therapy for two weeks- a significantly longer time than most people leave whitening strips on- after which researchers measured the increasing numbers of remaining proteins. When compared against untreated teeth, the whitened teeth evidenced a loss of protein, has said that if hydrogen peroxide can probe the enamel, then it was able shattering non-collagen proteins in the teeth.
The second time around, researchers characterized how H2O2 breaks down various proteins by mingling different concentrations of it with albumin protein, the main protein of human blood plasma, for 1 hour. When compared with the restrain, they also found that H2O2 breaks down important proteins even in concentrations similar to those used in whitening strips.
Lastly, researchers considered pure collagen with hydrogen peroxide and analyzed it applying a process called gel electrophoresis in order to imagine the protein. Similarly, researchers found that “hydrogen peroxide, even at the concentration used in the whitening airstrip, can damage the collagen in the dentin provided that the H2O2 can probe to the dentin in the teeth, ” they wrote.
“Our develops showed that care with hydrogen peroxide concentrations similar to those found in whitening airstrips is sufficient to attain the original collagen protein disappear, which is presumably due to the formation of numerous smaller fragments, ” said Keenan.
Researchers are quick to caution that their experiment did not consider whether collagen and other proteins can be regenerated, so it’s unknown if this impair is permanent. Additionally, it is important to note that the “research is just completed and there is not yet a peer-reviewed paper available, ” according to a conference spokesperson. As such, certain limitations may not have been considered.